Research

Hearing loss and mental health

My meta-analysis of randomized controlled trials asked whether hearing aids reduce depressive symptoms (poster, American Psychological Association Convention, Washington, DC, 2023). On a 2025 poster on mental health after unilateral hearing loss (second author), I ran the propensity-score matching and Cox analyses, made the poster and presented it in Rome at the International Congress on the Education of the Deaf. I am a co-author of a three-year retrospective cohort study of depression, anxiety and insomnia in 8964 adult cochlear implant users (Cochlear Implants International, 2026).

Papers and presentations

• Liu T-H, Liu C-Y. Unseen Struggles: The Hidden Mental Health Toll of Unilateral Hearing Loss [Poster 428]. 24th International Congress on the Education of the Deaf (ICED), Rome, Italy, July 2025.
• Liu C-Y, Liu C-J, Liu H-T, Liu T-H. The effect of hearing aids on depressive symptoms: meta-analysis of randomized controlled trials [Poster]. American Psychological Association Convention, Washington, DC, August 2023.
• Kuo K-W, Liu T-H, Liu C-Y, Liu C-J. Effects of cochlear implants on depression, anxiety, and insomnia in adults with bilateral sensorineural hearing loss: a three-year retrospective cohort study of 8964 cochlear implant users. Cochlear Implants International. 2026;27(1):2-10. doi:10.1080/14670100.2025.2602323.

Medication outcomes in electronic health records

A cohort study I co-authored compared the risk of falls and delirium between dual orexin receptor antagonists and benzodiazepines or Z-drugs in older adults with dementia (Translational Psychiatry, 2026). It used TriNetX data with propensity-score matching and survival analysis. Two other papers look at GLP-1RA versus metformin for diabetes prevention in patients treated with antipsychotics, and at tirzepatide use and suicidal ideation in people with obesity and major depressive disorder.

Papers and presentations

• Liu T-H, Chu C-C, Liu C-Y, Wu J-Y, Tsai Y-W, Chang H-A, Lai C-C. Risk of falls and delirium associated with dual orexin receptor antagonists versus benzodiazepines and Z-drugs in older adults with dementia. Translational Psychiatry. 2026. doi:10.1038/s41398-026-04394-8.
• Liu T-H, Lee C-H, Liu C-Y, Wu J-Y, Tsai Y-W, Kao P-H, Lai C-C. Effectiveness of GLP-1RA vs metformin for diabetes prevention in antipsychotic-treated patients. European Neuropsychopharmacology. 2026;110:112853. doi:10.1016/j.euroneuro.2026.112853.
• Liu T-H, Chu C-C, Liu C-Y, Wu J-Y, Tsai Y-W, Chang H-A, Lai C-C. Association between tirzepatide use and risk of suicidal ideation among individuals with obesity and major depressive disorder. Translational Psychiatry. In press (accepted September 2026).
• Liu T-H, Liu C-Y, Liu H-T, Liu C-J. Risk of falls and delirium associated with dual orexin receptor antagonists versus benzodiazepines in older adults with dementia [Poster]. WCAP 2026, Sapporo, Japan, October 2026.

Meta-analysis of interventions

I am co-first author of a dose-response meta-analysis with trial sequential analysis of laughter therapy for depression and anxiety (Journal of Psychiatric Research, 2026). A second dose-response meta-analysis covered vitamin D supplementation in patients with depression (Frontiers in Nutrition, 2026). My master's thesis was a set of meta-analyses of phonological-based and auditory-based training for school-aged children with reading difficulties, and I submitted the manuscript to Educational Psychology Review in March 2026.

Papers and presentations

• Liu C-Y*, Liu T-H*, Huang C-W, Lai C-C, Lin C-H, Su K-P. Effects of laughter therapy on depression and anxiety: a dose-response meta-analysis with trial sequential analysis. Journal of Psychiatric Research. 2026;199:50-61. doi:10.1016/j.jpsychires.2026.04.006. *Equal contribution.
• Liu H-H, Liu T-H, Liu C-Y, Wu J-Y, Lin C-H, Lai C-C. Efficacy of vitamin D supplementation in patients diagnosed with depression: a dose-response meta-analysis of randomized controlled trials. Frontiers in Nutrition. 2026;13:1772451. doi:10.3389/fnut.2026.1772451.
• Liu C-Y, Chen C-H, Wang H-L, Wang Y-H. Meta-analyses of phonological-based and auditory-based training effects on school-aged children with reading difficulties. Submitted to Educational Psychology Review, March 2026.
• Liu C-Y, Liu T-H, Liu H-T, Liu C-J. Effects of laughter therapy on depression and anxiety: dose-response meta-analysis with trial sequential analysis [Poster]. WCAP 2026, Sapporo, Japan, October 2026.
• Liu C-Y, Chen C-H, Wang H-L, Wang Y-H. Meta-analyses of phonological-based and auditory-based training effects on school-aged children with reading difficulties [Oral]. Association for Reading and Writing in Asia, Cebu, Philippines, February 2025.
• Liu C-Y, Wang Y-H. The effect of phonological-based intervention for school-aged children with developmental dyslexia: a meta-analysis [Poster]. American Speech-Language-Hearing Association Convention, Seattle, WA, December 2024.

Theory of mind and language in deaf and hard of hearing children

A longitudinal manuscript I co-authored, on spoken language, theory of mind and reading comprehension in deaf and hard of hearing children in Taiwan, was submitted to Deafness & Education International in September 2026. At the 11th World Congress of Asian Psychiatry (WCAP 2026) in Sapporo, I presented a poster on reducing linguistic bias in advanced theory-of-mind assessment for adolescents. A book chapter in production with Gallaudet University Press is a case study of a Taiwanese deaf teacher teaching primary arithmetic word problems.

Papers and presentations

• Liu C-Y, Liu H-T, Liu C-J, Liu T-H. Reducing linguistic bias in advanced theory-of-mind assessment [Poster]. 11th World Congress of Asian Psychiatry (WCAP 2026), Sapporo, Japan, October 2026.
• Liu H-T, Liu C-J, Liu C-Y, Squires B. Longitudinal relationships between spoken language, theory of mind, and reading comprehension in deaf and hard of hearing children in Taiwan. Submitted to Deafness & Education International, September 2026.
• Chen C-Y, Liu H-T, Liu C-Y, Andrews JF. "How much milk tea is in the tea bucket?" Case study of a Taiwanese deaf teacher teaching primary arithmetic word problems. In: Deaf Languaging and Translanguaging Across Asia. Gallaudet University Press; in production, expected Spring 2027.
• Liu H-T, Liu C-J, Liu C-Y. Longitudinal study of theory-of-mind development in children with hearing loss and children with typical hearing [Oral]. ICED, Rome, Italy, July 2025.
• Liu C-Y, Liu H-T, Liu C-J. Easy-to-read text with illustrations: generative AI innovations for Deaf and hard of hearing individuals [Poster]. ICED, Rome, Italy, July 2025.

Learning project

A learning project that builds an EEG analysis pipeline in Python with MNE on open data (Sleep-EDF and OpenNeuro ds004504). Levels 1 and 2 of 8 are complete; Level 3, power spectra by sleep stage, is in progress. Repository on GitHub